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Side-effects news

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Access to medicines and treatment
Groups to Global Fund, PEPFAR: Support switch from toxic treatment

The global health advocacy organisation HealthGAP and the two largest civil society organisations for people affected by HIV in Malawi have asked the country's government, the Global Fund for HIV, TB and Malaria, and PEPFAR to find a way to stop using the drug d4T (stavudine) in the HIV combination therapy it provides. Stavudine is far cheaper than its alternative, tenofovir, but causes severe and sigmatising side effects that have led to its being dropped in richer countries.

Published
16 August 2012
From
Science Spreaks
New and experimental HIV treatments
Dolutegravir matches raltegravir for people starting treatment

The novel integrase inhibitor dolutegravir worked as well as raltegravir (Isentress) at 48 weeks for treatment-naive people in the Phase III SPRING-2 study, according to a late-breaker

Published
27 July 2012
By
Liz Highleyman
Contraception
Does injectable hormonal contraception increase the risk of HIV infection?

The 19th International AIDS Conference (AIDS 2012) heard further contradictory evidence this week on whether hormonal contraceptives, especially injectable ones, raise the risk to women of acquiring

Published
27 July 2012
By
Gus Cairns
Side-effects
Early CNS toxicity with efavirenz often persists in London group

One fifth of London clinic members starting Atripla (efavirenz, tenofovir, and emtricitabine in one pill) had to switch therapy, almost always because of side effects. Efavirenz-related central nervous system (CNS) toxicity was the most common reason for stopping Atripla, and this toxicity often persisted well beyond a few weeks.

Published
17 July 2012
From
International AIDS Society
Side-effects
Diarrhoea remains a common problem in people with HIV

Diarrhoea remains common in people with HIV and usually has a non-infectious cause, according to a review article published in the online edition of Clinical Infectious Diseases. The

Published
06 July 2012
By
Michael Carter
Bone problems
High Dose Vitamin D Prevents Fractures

High doses of vitamin D prevent fractures in older people – as long as they take the substance regularly.

Published
05 July 2012
From
Medical News Today
Bone problems
Low bone density present in young men taking HIV therapy

HIV infection in young men is associated with reduced bone mineral density, US investigators report in the online edition of Clinical Infectious Diseases. Antiretroviral therapy based on a

Published
04 July 2012
By
Michael Carter
Bad science and bogus treatments
Sowetan villainizes life-saving treatment: Another “ARV boob” booby

Today the Sowetan carried the story of a woman with grotesquely overgrown breasts. The paper’s reason for her condition: ARVs in general. In a climate where close to 6 million people are living with HIV and will eventually need treatment, this kind of coverage is deeply misleading and unethical.

Published
18 June 2012
From
JournAIDS
Side-effects
South Africa: Stavudine Trial Causes Split

AIDS activists and researchers are at loggerheads over the planned South African trial of a lower dose version of the controversial antiretroviral stavudine, which has in the past been responsible for debilitating side-effects in HIV patients.

Published
11 June 2012
From
AllAfrica
Side-effects
European Medicines Agency boosts EU transparency with online publication of suspected side effect reports

Member States and the Agency release data on medicines in compliance with EudraVigilance access policy

Published
01 June 2012
From
European Medicines Agency press release
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